Michael S. Krangel, PhD

Michael S. Krangel, PhD, was appointed interim chair of the Department of Immunology on January 1, 2009.

Krangel received a BS in biochemistry from the State University of New York at Stony Brook in 1976. He did his graduate work in the Department of Biochemistry and Molecular Biology at Harvard University, receiving his PhD in 1982. He subsequently moved to the Cold Spring Harbor Laboratory for postdoctoral training.  In 1985, Krangel joined the faculty at Harvard Medical School, first as instructor and then as assistant professor of pathology, housed within the Division of Tumor Virology at the Dana-Farber Cancer Institute. There he began his studies on T cell receptors and the organization and regulation of T cell receptor genes. He moved to Duke University Medical Center in 1990, initially as associate professor of microbiology and immunology. 

He is currently professor of immunology and also serves as the director of Graduate Studies in Immunology. Krangel’s current work focuses on T lymphocyte development in the thymus, with a specific emphasis on the genetic and epigenetic mechanisms that regulate V(D)J recombination and the assembly of T cell receptor genes.